3-(5-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #155123
fingerprint
CAS Number 2408391-89-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.13 g/mol
Formula C₁₃H₁₀BrFN₂O₃
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. The compound's ability to recruit specific proteins for ubiquitination and subsequent degradation allows for precise control over disease-related protein levels. It is also explored in the design of molecular glues that enhance interactions between E3 ligase and target proteins. Due to its bromo and fluoro substituents, it offers favorable reactivity and binding properties for further chemical modifications in drug discovery programs.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,480.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB