1-(tert-Butyl)4-(1,3-dioxoisoindolin-2-yl)piperidine-1,4-dicarboxylate
97%
Reagent
Code: #154903
CAS Number
1872262-73-1
blur_circular Chemical Specifications
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Molecular Information
Weight
374.394 g/mol
Formula
C₁₉H₂₂N₂O₆
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active compounds such as proteolysis-targeting chimeras (PROTACs). Its structure allows for the incorporation of E3 ligase ligands, enabling targeted protein degradation. Commonly employed in medicinal chemistry for constructing bifunctional molecules that link a target protein binder to an E3 ubiquitin ligase recruiter. Also utilized in research settings for developing novel therapeutics in oncology and neurodegenerative diseases.
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