5-Bromo-2-(2,6-Dioxopiperidin-3-Yl)-4-Fluoroisoindoline-1,3-Dione

98%

Reagent Code: #153977
fingerprint
CAS Number 2740657-28-5

science Other reagents with same CAS 2740657-28-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 355.12 g/mol
Formula C₁₃H₈BrFN₂O₄
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, especially cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also employed in studies involving molecular glues and ubiquitin-proteasome system modulation due to its ability to induce degradation of specific disease-related proteins.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿15,000.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
5-Bromo-2-(2,6-Dioxopiperidin-3-Yl)-4-Fluoroisoindoline-1,3-Dione
No image available

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, especially cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also emplo

Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, especially cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also employed in studies involving molecular glues and ubiquitin-proteasome system modulation due to its ability to induce degradation of specific disease-related proteins.

Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...