3-(4-Bromo-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione

97%

Reagent Code: #151434
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CAS Number 2093386-30-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 337.17 g/mol
Formula C₁₄H₁₃BrN₂O₃
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The compound's bromo and isoindolinone groups facilitate conjugation with target-binding ligands, enhancing degradation of disease-related proteins. Also explored in medicinal chemistry for optimizing pharmacokinetic properties in small molecule therapeutics.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,500.00
inventory 250mg
10-20 days ฿7,630.00
inventory 1g
10-20 days ฿22,290.00

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