3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #149966
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CAS Number 2438243-28-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.13 g/mol
Formula C₁₃H₁₀BrFN₂O₃
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for optimizing pharmacokinetic properties in preclinical candidates due to its favorable solubility and stability profile.

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Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿2,200.00
inventory 250mg
10-20 days ฿8,100.00
inventory 1g
10-20 days ฿28,170.00

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