3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #149966
fingerprint
CAS Number 2438243-28-6

science Other reagents with same CAS 2438243-28-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.13 g/mol
Formula C₁₃H₁₀BrFN₂O₃
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for optimizing pharmacokinetic properties in preclinical candidates due to its favorable solubility and stability profile.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿2,200.00
inventory 250mg
10-20 days ฿8,100.00
inventory 1g
10-20 days ฿28,170.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
No image available

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for opti

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for optimizing pharmacokinetic properties in preclinical candidates due to its favorable solubility and stability profile.

Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...