3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

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Reagent Code: #149966
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CAS Number 2438243-28-6

science Other reagents with same CAS 2438243-28-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.13 g/mol
Formula C₁₃H₁₀BrFN₂O₃
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for optimizing pharmacokinetic properties in preclinical candidates due to its favorable solubility and stability profile.

Available Sizes & Pricing

Size Availability Unit Price Quantity
50mg
10-20 days ฿2,200.00
250mg
10-20 days ฿8,100.00
1g
10-20 days ฿28,170.00

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3-(7-Bromo-4-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for opti

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo and fluoro substituents allow further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also investigated for optimizing pharmacokinetic properties in preclinical candidates due to its favorable solubility and stability profile.

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