3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #149953
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CAS Number 2304513-76-4

science Other reagents with same CAS 2304513-76-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 323.14 g/mol
Formula C₁₃H₁₁BrN₂O₃
badge Registry Numbers
MDL Number MFCD32667217
inventory_2 Storage & Handling
Storage Room temperature, airtight, dry

description Product Description

Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including PROTACs (proteolysis-targeting chimeras), which are emerging as powerful tools for treating cancers and other diseases by selectively degrading disease-causing proteins. Its structure enables effective binding to cereblon, making it valuable in designing molecules with enhanced selectivity and potency in oncology research.

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Test Parameter Specification
Appearance Gray to Gray-Purple Powder
Purity 97.5-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿870.00
inventory 1g
10-20 days ฿2,270.00
inventory 5g
10-20 days ฿9,990.00
inventory 10g
10-20 days ฿19,870.00
inventory 25g
10-20 days ฿43,920.00

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3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including PROTACs (proteolysis-targeting chimeras), which are emerging as powerful tools for treating cancers and other diseases by selectively degrading disease-causing proteins. Its structure enables effective binding to cereblon, making it valuable in designing molecules with enhanced selectivity and

Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including PROTACs (proteolysis-targeting chimeras), which are emerging as powerful tools for treating cancers and other diseases by selectively degrading disease-causing proteins. Its structure enables effective binding to cereblon, making it valuable in designing molecules with enhanced selectivity and potency in oncology research.

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