Used as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and immunomodulatory treatments. It is also employed in research for degrading disease-causing proteins by hijacking the cell’s ubiquitin-proteasome system. Due to its bromo-functionalized isoindolinone core, it allows for further chemical modifications, facilitating the creation of novel drug candidates in oncology and neurodegenerative disease research.