3-(7-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione

99%

Reagent Code: #148840
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CAS Number 2229976-08-1

science Other reagents with same CAS 2229976-08-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 323.15 g/mol
Formula C₁₃H₁₁BrN₂O₃
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo substituent allows further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery.

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Test Parameter Specification
Appearance Grey solid
Purity (%) 98.5-100%
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿690.00
inventory 1g
10-20 days ฿2,222.00
inventory 5g
10-20 days ฿14,860.00

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3-(7-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
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Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo substituent allows further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery.

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer and inflammatory diseases. The bromo substituent allows further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery.

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