Used primarily in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. The iodine moiety allows for further functionalization via cross-coupling reactions, facilitating the creation of diverse compound libraries for drug discovery. Also employed in studies involving molecular glues and immunomodulatory agents due to its ability to alter protein-protein interactions within cells.