4-(But-3-yn-1-ylamino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

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Reagent Code: #131057
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CAS Number 2154356-73-5

science Other reagents with same CAS 2154356-73-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 325.32 g/mol
Formula C₁₇H₁₅N₃O₄
thermostat Physical Properties
Boiling Point 617.4±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.449±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used primarily in pharmaceutical research, this compound functions as a PROTAC (Proteolysis Targeting Chimera) linker. It connects a target-binding ligand to an E3 ubiquitin ligase recruiter, enabling targeted protein degradation. Its structure allows selective degradation of disease-related proteins, making it valuable in oncology and inflammatory disease studies. The alkyne group provides a site for further conjugation via click chemistry, facilitating modular drug design and rapid compound optimization in drug discovery pipelines.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿25,540.00
inventory 250mg
10-20 days ฿9,460.00

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4-(But-3-yn-1-ylamino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
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Used primarily in pharmaceutical research, this compound functions as a PROTAC (Proteolysis Targeting Chimera) linker. It connects a target-binding ligand to an E3 ubiquitin ligase recruiter, enabling targeted protein degradation. Its structure allows selective degradation of disease-related proteins, making it valuable in oncology and inflammatory disease studies. The alkyne group provides a site for further conjugation via click chemistry, facilitating modular drug design and rapid compound optimization in drug discovery pipelines.
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