3-(4-Ethynyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione
98%
Reagent
Code: #130240
CAS Number
1416990-26-5
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
268.27 g/mol
Formula
C₁₅H₁₂N₂O₃
badge
Registry Numbers
MDL Number
MFCD34186149
thermostat
Physical Properties
Boiling Point
580.5±50.0 °C(Predicted)
inventory_2
Storage & Handling
Density
1.41±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and other diseases involving protein dysregulation. It is also explored for improving pharmacokinetic properties in drug design due to its stable isoindolinone core and functional handles for chemical modification.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB