3-(4-Ethynyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #130240
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CAS Number 1416990-26-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 268.27 g/mol
Formula C₁₅H₁₂N₂O₃
badge Registry Numbers
MDL Number MFCD34186149
thermostat Physical Properties
Boiling Point 580.5±50.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.41±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and other diseases involving protein dysregulation. It is also explored for improving pharmacokinetic properties in drug design due to its stable isoindolinone core and functional handles for chemical modification.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿12,540.00
inventory 100mg
10-20 days ฿21,300.00
inventory 250mg
10-20 days ฿36,200.00

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