3-(1-Oxo-4-(prop-2-yn-1-ylamino)isoindolin-2-yl)piperidine-2,6-dione

97%

Reagent Code: #130140
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CAS Number 2589697-32-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 297.31 g/mol
Formula C₁₆H₁₅N₃O₃
badge Registry Numbers
MDL Number MFCD32903420
thermostat Physical Properties
Boiling Point 634.3±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.406±0.06 g/cm3(Predicted)
Storage Room temperature, light-proof, inert gas

description Product Description

Used primarily in pharmaceutical research, this compound functions as a cereblon E3 ligase modulator. It plays a key role in targeted protein degradation, particularly in the development of PROTACs (proteolysis-targeting chimeras). By binding to cereblon, it facilitates the ubiquitination and subsequent degradation of specific disease-related proteins. Its structure enables conjugation with other targeting ligands, making it valuable in oncology and immunomodulatory drug design. It is especially explored for its potential in treating hematological cancers and resistant tumor types.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,460.00
inventory 250mg
10-20 days ฿7,580.00
inventory 1g
10-20 days ฿20,450.00

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