Boc-C5-O-C5-O-C6-Cl is widely utilized in the development of PROTACs (Proteolysis Targeting Chimeras), which are innovative molecules designed to target and degrade specific proteins within cells. This compound serves as a crucial linker, connecting the target-binding ligand to the E3 ubiquitin ligase ligand in the PROTAC structure. Its flexible and stable design allows for optimal spatial arrangement, ensuring efficient protein degradation. This linker is particularly valuable in drug discovery and therapeutic research, enabling the creation of molecules that can selectively eliminate disease-causing proteins, such as those involved in cancer, neurodegenerative disorders, and other pathological conditions. Its application supports the advancement of targeted protein degradation as a promising strategy in modern medicine.