VH032-phenol is primarily utilized in the field of medicinal chemistry and drug discovery, particularly in the development of proteolysis-targeting chimeras (PROTACs). These molecules are designed to degrade specific proteins within cells, offering a novel approach to targeting disease-causing proteins that are traditionally considered "undruggable." VH032-phenol serves as a key ligand in the construction of PROTACs, binding to E3 ubiquitin ligases, which are crucial for the ubiquitination and subsequent degradation of target proteins. Its application is especially significant in cancer research, where it aids in the degradation of oncogenic proteins, potentially leading to new therapeutic strategies. Additionally, it is used in biochemical studies to explore protein-protein interactions and the mechanisms of ubiquitin-proteasome system, providing insights into cellular processes and disease pathways.