(S,R,S)-AHPC-PEG3-propionic acid
≥95%
blur_circular Chemical Specifications
description Product Description
Used primarily in the field of targeted protein degradation, this compound is a key component in the development of PROTACs (Proteolysis Targeting Chimeras). It facilitates the recruitment of E3 ubiquitin ligases to specific proteins, leading to their ubiquitination and subsequent degradation by the proteasome. This mechanism is particularly valuable in cancer research, where it helps in the selective elimination of oncogenic proteins. Additionally, it is employed in studying protein function and regulation, providing insights into cellular processes and potential therapeutic targets. The PEG3 spacer enhances solubility and flexibility, improving the compound's efficiency in biological systems.
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