Thalidomide-O-COOH is primarily utilized in the field of medicinal chemistry for its potential therapeutic properties. It is often explored as a derivative of thalidomide, aiming to enhance its efficacy while reducing adverse effects. This compound is investigated for its anti-inflammatory, immunomodulatory, and anti-angiogenic activities, making it a candidate for treating conditions such as certain cancers, autoimmune diseases, and inflammatory disorders. Researchers are particularly interested in its ability to inhibit tumor growth and modulate the immune response, which could lead to innovative treatments for diseases like multiple myeloma and leprosy. Additionally, its modified structure may offer improved pharmacokinetic properties, such as better solubility or targeted delivery, enhancing its clinical applicability. Ongoing studies focus on optimizing its therapeutic potential and minimizing toxicity for safer and more effective use in medical applications.