Thalidomide-O-C2-acid is primarily utilized in the field of medicinal chemistry and pharmaceutical research. It serves as a key intermediate in the synthesis of various thalidomide analogs, which are investigated for their potential therapeutic properties. These analogs are often explored for their anti-inflammatory, immunomodulatory, and anti-angiogenic effects, making them relevant in the treatment of conditions such as multiple myeloma, leprosy, and certain autoimmune diseases. Additionally, its structural modification allows researchers to fine-tune the pharmacokinetic and pharmacodynamic properties of derived compounds, enhancing their efficacy and reducing potential side effects. This chemical is also valuable in studying the mechanisms of action of thalidomide-like drugs, particularly their interaction with cellular targets such as cereblon, a protein involved in protein degradation pathways.