3-(5-Nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #220553
fingerprint
CAS Number 1198787-23-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 289.24 g/mol
Formula C₁₃H₁₁N₃O₅
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and inflammatory diseases. It is also explored for improving pharmacokinetic properties in drug design due to its stable isoindolinone core and functional handles for chemical modification.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿6,800.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB