OC000459 is primarily utilized in research settings to study its effects on inflammatory diseases, particularly those involving the respiratory system. It acts as a selective antagonist for the CRTH2 receptor, which plays a significant role in mediating allergic responses. By inhibiting this receptor, it helps researchers understand the mechanisms of asthma, allergic rhinitis, and other inflammatory conditions. Additionally, it is explored for its potential therapeutic applications in managing chronic obstructive pulmonary disease (COPD) and eosinophilic disorders. Its ability to modulate immune responses makes it a valuable tool in developing targeted treatments for inflammation-driven diseases.