(R)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
97%
Reagent
Code: #76158
CAS Number
536747-87-2
blur_circular Chemical Specifications
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Molecular Information
Weight
251.23 g/mol
Formula
C₁₀H₁₅F₂NO₄
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Registry Numbers
MDL Number
MFCD08272893
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
This compound is primarily used in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structure, featuring a tert-butoxycarbonyl (Boc) protecting group and a difluoropyrrolidine moiety, makes it valuable for the development of protease inhibitors and other drug candidates. The Boc group can be easily removed under mild acidic conditions, allowing for further functionalization of the molecule. The difluoropyrrolidine core is particularly significant in medicinal chemistry due to its ability to enhance the metabolic stability and bioavailability of drug molecules. Additionally, this compound is utilized in peptide synthesis and the creation of peptidomimetics, which are designed to mimic the biological activity of peptides while offering improved stability and efficacy. Its applications extend to research in organic synthesis, where it serves as a building block for the preparation of complex molecules with potential therapeutic properties.
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