NS8593 hydrochloride is primarily used in research settings to study the role of specific ion channels in cellular processes. It acts as a potent and selective inhibitor of SK (small conductance calcium-activated potassium) channels, which are involved in regulating neuronal excitability and smooth muscle contraction. Researchers utilize this compound to investigate the physiological and pathological roles of SK channels in various tissues, including the nervous system and cardiovascular system. Its application extends to exploring potential therapeutic targets for conditions such as atrial fibrillation, epilepsy, and hypertension. Additionally, NS8593 hydrochloride is employed in electrophysiological studies to understand the mechanisms underlying channel function and modulation, aiding in the development of novel pharmacological interventions.