QX 222 is primarily used in research settings as a selective blocker of certain types of potassium channels, particularly those involved in neural signaling. Its application is significant in studying the electrical properties of neurons and understanding the role of potassium channels in various physiological processes. Researchers utilize it to investigate conditions related to neural excitability, such as epilepsy or neuropathic pain, by selectively inhibiting specific potassium currents. This helps in elucidating the mechanisms underlying these disorders and in the development of targeted therapeutic strategies. Additionally, QX 222 is employed in electrophysiological experiments to isolate and study specific ion channel contributions to cellular activity, aiding in the broader understanding of neural function and dysfunction.