Used in research for its potent and selective inhibition of the Kv7.2/7.3 potassium channels, making it a valuable tool for studying neuronal excitability and potential therapeutic interventions in hyperexcitability disorders such as epilepsy and neuropathic pain. It helps modulate M-current activity in neurons, allowing scientists to investigate the role of these ion channels in synaptic transmission and network behavior. Due to its selectivity, it is preferred over less specific potassium channel modulators in preclinical studies.