CCT251545 is primarily used in research settings as a potent and selective inhibitor of the Wnt pathway, which plays a critical role in cell signaling and development. Its application is significant in studying cancer biology, particularly in understanding the mechanisms of Wnt-driven tumors. Researchers utilize this compound to explore potential therapeutic strategies for cancers such as colorectal cancer, where Wnt signaling is often dysregulated. Additionally, CCT251545 serves as a valuable tool in drug discovery efforts, helping to identify and validate new targets within the Wnt pathway. Its use in preclinical studies aids in evaluating the efficacy and safety of novel cancer treatments.