WAY-262611 is a potent and selective small molecule inhibitor of tankyrase 1 and 2 (TNKS1/2), enzymes involved in the Wnt/β-catenin signaling pathway. It stabilizes Axin, leading to β-catenin degradation and inhibition of canonical Wnt signaling. Primarily used in research settings, it helps study Wnt pathway dysregulation in diseases such as cancer, fibrosis, osteoporosis, and metabolic disorders. Researchers utilize it in cell-based assays and animal models to explore therapeutic potential for Wnt-related conditions, aiding in drug discovery and understanding developmental biology.