Used as a solid-supported reagent in organic synthesis, particularly for scavenging acids and acidic byproducts. Its cross-linked structure provides mechanical stability and insolubility, allowing easy separation from reaction mixtures. Commonly employed in combinatorial chemistry and parallel synthesis for purification of amine-containing compounds. Also utilized in catalysis, where it acts as a base catalyst or a support for metal catalysts. Finds application in analytical chemistry for sample cleanup and in the development of sensors due to its ability to interact with various analytes through coordination or acid-base interactions.