2,3',4,5-Tetrachlorobiphenyl is primarily used in research settings to study the environmental impact and toxicological effects of polychlorinated biphenyls (PCBs). It serves as a model compound to understand the behavior, persistence, and degradation of PCBs in ecosystems. Researchers analyze its interactions with biological systems to assess potential health risks, including its role as an endocrine disruptor and its effects on the immune and nervous systems. Additionally, this chemical is utilized in the development of remediation techniques to remove or neutralize PCB contamination in soil and water. Its properties also make it relevant in studies focused on the bioaccumulation and biomagnification of chlorinated compounds in food chains.