Used as a protected macrocyclic amine ligand in coordination chemistry, particularly in the synthesis of metal complexes for catalysis and medical imaging. Its sulfonamide-protected structure allows selective deprotection to form tetraazamacrocycles that bind transition metals like gadolinium, copper, or zinc. These metal complexes are valuable in MRI contrast agents and radiopharmaceuticals due to their high stability and selectivity. Also employed in the development of sensors and functional materials where controlled metal ion binding is required.