1-Boc-3-chloro-piperidine
97%
Reagent
Code: #152243
CAS Number
885275-01-4
blur_circular Chemical Specifications
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Molecular Information
Weight
219.708 g/mol
Formula
C₁₀H₁₈ClNO₂
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Registry Numbers
MDL Number
MFCD08059310
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Physical Properties
Boiling Point
289.7 °C at 760 mmHg
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Storage & Handling
Density
1.11 g/cm3
Storage
2-8°C, Sealed
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) where a protected piperidine scaffold is required. The Boc (tert-butoxycarbonyl) group provides amine protection during multi-step reactions, allowing selective functionalization at other sites. The chloro substituent serves as a reactive handle for nucleophilic substitution or cross-coupling reactions, enabling the introduction of various side chains. Commonly employed in the preparation of centrally acting agents, including those targeting neurological and psychiatric disorders. Its structure is valuable in medicinal chemistry for constructing constrained analogs of bioactive molecules.
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