tert-Butyl (3S,4R)-4-fluoro-3-hydroxypiperidine-1-carboxylate
97%
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description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated piperidine-containing drugs. Its stereochemistry makes it valuable for constructing bioactive molecules with high enantioselectivity. Commonly employed in the preparation of central nervous system agents, including certain antipsychotics and antidepressants. The tert-butyl carbamate (Boc) group allows for easy protection of the nitrogen during multi-step syntheses, while the hydroxyl and fluoro substituents provide sites for further functionalization. Widely utilized in medicinal chemistry for structure-activity relationship studies due to its conformational rigidity and polarity.
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