tert-Butyl ((3R,4S)-3-fluoropiperidin-4-yl)carbamate
97%
Reagent
Code: #151139
CAS Number
1630815-57-4
blur_circular Chemical Specifications
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Molecular Information
Weight
218.27 g/mol
Formula
C₁₀H₁₉FN₂O₂
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Registry Numbers
MDL Number
MFCD18632653
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Physical Properties
Boiling Point
313.3±42.0 °C(Predicted)
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Storage & Handling
Density
1.08±0.1 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its chiral structure with fluorine substitution enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in the preparation of protease inhibitors and receptor modulators due to the constrained piperidine scaffold, which improves pharmacokinetic properties. The tert-butyloxycarbonyl (Boc) protecting group allows for selective amine functionalization during multi-step syntheses, making it valuable in medicinal chemistry and process development.
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