tert-Butyl 3-(aminomethyl)-4,4-difluoropiperidine-1-carboxylate
98%
Reagent
Code: #150674
CAS Number
1303973-27-4
blur_circular Chemical Specifications
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Molecular Information
Weight
250.29 g/mol
Formula
C₁₁H₂₀F₂N₂O₂
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Registry Numbers
MDL Number
MFCD18909857
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Storage & Handling
Storage
-20°C, sealed, light-proof, inert gas
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its structure supports the creation of bioactive molecules due to the presence of a protected amine and a fluorinated piperidine ring, which can enhance metabolic stability and blood-brain barrier penetration. Commonly employed in medicinal chemistry for optimizing drug candidates targeting neurological disorders, including anxiety, depression, and psychosis. Also utilized in the preparation of selective receptor modulators, where the tert-butyl carbamate group allows for controlled amine reactivity during multi-step synthesis.
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