1-Boc-5,5-difluoro-3-(hydroxymethyl)piperidine

≥95%

Reagent Code: #150648
fingerprint
CAS Number 1262412-64-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 251.27 g/mol
Formula C₁₁H₁₉F₂NO₃
badge Registry Numbers
MDL Number MFCD16875553
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated analogs of bioactive molecules. The presence of the difluoro group enhances metabolic stability and membrane permeability, making it valuable in medicinal chemistry. The Boc-protected amine allows for selective deprotection and further functionalization, enabling controlled stepwise synthesis. The hydroxymethyl group provides a handle for derivatization, such as esterification or ether formation, facilitating the construction of complex drug candidates. Commonly employed in the preparation of central nervous system agents and enzyme inhibitors where fluorine substitution improves pharmacokinetic properties.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿25,060.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB