tert-Butyl (4R)-4-amino-3,3-difluoropiperidine-1-carboxylate
95%
Reagent
Code: #150211
CAS Number
1820679-70-6
blur_circular Chemical Specifications
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Molecular Information
Weight
236.26 g/mol
Formula
C₁₀H₁₈F₂N₂O₂
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Registry Numbers
MDL Number
MFCD30386986
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Storage & Handling
Storage
2-8°C, dry, sealed, and protected from light
description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of biologically active compounds targeting central nervous system disorders and metabolic diseases. Its protected amine and fluorinated piperidine structure make it valuable in medicinal chemistry for enhancing metabolic stability and improving binding selectivity. Commonly employed in the preparation of protease inhibitors and receptor modulators where stereochemistry and fluorination play critical roles in activity. The tert-butyl carbamate (Boc) group allows for easy deprotection under mild acidic conditions, enabling efficient incorporation into complex drug molecules during multi-step synthesis.
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