tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate
95%
Reagent
Code: #149779
CAS Number
1334414-00-4
blur_circular Chemical Specifications
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Molecular Information
Weight
218.27 g/mol
Formula
C₁₀H₁₉FN₂O₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents and kinase inhibitors. Its structure supports the construction of bioactive molecules due to the presence of a protected amine and a fluorinated piperidine ring, which enhances metabolic stability and membrane permeability. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies, especially in optimizing drug candidates targeting neurological disorders and cancer. The tert-butyl carbamate (Boc) protection allows for selective functionalization, making it valuable in multi-step organic syntheses.
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