1-(tert-Butoxycarbonyl)-3,3-difluoro-4,4-dihydroxypiperidine
≥97%(GC)
Reagent
Code: #149397
CAS Number
1067914-83-3
blur_circular Chemical Specifications
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Molecular Information
Weight
253.2431 g/mol
Formula
C₁₀H₁₇F₂NO₄
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Registry Numbers
MDL Number
MFCD18072968
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Storage & Handling
Storage
2-8℃
description Product Description
Used in pharmaceutical synthesis as a protected intermediate for building fluorinated piperidine scaffolds. The tert-butoxycarbonyl (Boc) group provides amine protection during peptide coupling or heterocycle formation, while the difluoro and dihydroxy moieties enhance metabolic stability and influence conformation in drug candidates. Commonly employed in the development of bioactive molecules targeting central nervous system disorders and enzyme inhibitors where fluorination improves blood-brain barrier penetration and binding affinity. Its structure supports stereocontrolled transformations, making it valuable in medicinal chemistry for optimizing pharmacokinetic properties.
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