tert-Butyl 3,3-difluoro-4-oxopiperidine-1-carboxylate
97%
Reagent
Code: #148421
CAS Number
1215071-17-2
blur_circular Chemical Specifications
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Molecular Information
Weight
235.23 g/mol
Formula
C₁₀H₁₅F₂NO₃
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Registry Numbers
MDL Number
MFCD16140378
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Physical Properties
Boiling Point
274.7±40.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure supports the creation of conformationally restricted analogs, enhancing metabolic stability and receptor selectivity. Commonly employed in medicinal chemistry for constructing fluorinated piperidine derivatives, which are valuable in improving pharmacokinetic properties such as membrane permeability and resistance to oxidative degradation. Also utilized in the preparation of enzyme inhibitors and receptor modulators where fluorination plays a key role in potency enhancement.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White Powder |
| Purity (%) | 96.5-100 |
| NMR | Conforms to Structure |
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