1-Benzyl-3,3-difluoropiperidin-4-one
97%
Reagent
Code: #148398
CAS Number
1039741-54-2
blur_circular Chemical Specifications
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Molecular Information
Weight
225.24 g/mol
Formula
C₁₂H₁₃F₂NO
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Registry Numbers
MDL Number
MFCD15526740
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Physical Properties
Boiling Point
291.0±40.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its structure supports the creation of potent modulators of neurotransmitter receptors, making it valuable in drug discovery for neurological and psychiatric disorders. The difluorinated piperidinone core enhances metabolic stability and membrane permeability, which improves bioavailability in final drug formulations. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity.
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