1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid
≥95%
Reagent
Code: #148287
CAS Number
1303972-81-7
blur_circular Chemical Specifications
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Molecular Information
Weight
265.25 g/mol
Formula
C₁₁H₁₇F₂NO₄
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Registry Numbers
MDL Number
MFCD18909780
thermostat
Physical Properties
Boiling Point
356.4±42.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules targeting central nervous system disorders and metabolic diseases. Its structure allows for selective modification, making it valuable in medicinal chemistry for constructing drug candidates with improved metabolic stability and binding affinity. Commonly employed in the preparation of small-molecule inhibitors and receptor modulators where the difluorinated piperidine moiety enhances pharmacokinetic properties. Also utilized in solid-phase and solution-phase peptide-like synthesis due to the presence of the carboxylic acid and protected amine functional groups, enabling sequential coupling reactions.
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