1-(tert-Butoxycarbonyl)-5-fluoropiperidine-3-carboxylic acid
≥95%
Reagent
Code: #148126
CAS Number
1241725-64-3
blur_circular Chemical Specifications
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Molecular Information
Weight
247.26 g/mol
Formula
C₁₁H₁₈FNO₄
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Registry Numbers
MDL Number
MFCD17015060
thermostat
Physical Properties
Boiling Point
817.5±75.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated piperidine-containing drugs. Its structure supports the construction of bioactive molecules with improved metabolic stability and binding affinity. Commonly employed in medicinal chemistry for the preparation of protease inhibitors and central nervous system agents. The Boc-protected amine allows for selective reactions at other functional groups, making it valuable in multi-step organic syntheses. The fluorine atom enhances lipophilicity and membrane permeability, which is beneficial in drug design for optimizing pharmacokinetic properties.
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