1-Boc-4-Fluoro-4-(hydroxymethyl)piperidine
97%
Reagent
Code: #145354
CAS Number
614730-97-1
blur_circular Chemical Specifications
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Molecular Information
Weight
233.28 g/mol
Formula
C₁₁H₂₀FNO₃
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Registry Numbers
MDL Number
MFCD08062513
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Physical Properties
Boiling Point
311°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of centrally acting agents such as antidepressants, antipsychotics, and other neuroactive drugs. The presence of both a fluoro and hydroxymethyl group on the piperidine ring allows for selective modifications, enhancing metabolic stability and receptor binding affinity. The Boc-protected amine enables controlled deprotection and coupling in multi-step syntheses, making it valuable in medicinal chemistry for building complex molecules with high purity and yield. Commonly employed in research settings for structure-activity relationship (SAR) studies.
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