1-Boc-piperidine-3-carboxaldehyde
97%
Reagent
Code: #143498
CAS Number
118156-93-7
blur_circular Chemical Specifications
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Molecular Information
Weight
213.28 g/mol
Formula
C₁₁H₁₉NO₃
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Registry Numbers
MDL Number
MFCD02179020
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of active pharmaceutical ingredients (APIs) that require functionalized piperidine scaffolds. Its aldehyde group allows for further chemical transformations such as reductive amination or nucleophilic addition, enabling the construction of complex nitrogen-containing molecules. Commonly employed in medicinal chemistry for drug discovery programs, especially in the design of central nervous system (CNS) agents, kinase inhibitors, and bioactive molecules where a substituted piperidine ring enhances pharmacokinetic properties. The Boc-protected amine ensures selective reactivity and stability during multi-step syntheses, making it valuable in solid-phase and solution-phase peptide-like compound assembly.
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