tert-Butyl 3,3-difluoro-4-formylpiperidine-1-carboxylate
97%
Reagent
Code: #131306
CAS Number
1373503-65-1
blur_circular Chemical Specifications
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Molecular Information
Weight
249.25 g/mol
Formula
C₁₁H₁₇F₂NO₃
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Registry Numbers
MDL Number
MFCD22199367
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Storage & Handling
Storage
-20°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated drug candidates. The aldehyde group allows for further functionalization through reactions such as reductive amination or Wittig reactions, enabling the construction of complex molecular architectures. The tert-butyl carbamate (Boc) group provides amine protection during multi-step syntheses, ensuring selective reactivity. Its piperidine core with geminal difluoro substitution enhances metabolic stability and membrane permeability in bioactive molecules, making it valuable in medicinal chemistry for CNS-targeted drugs and enzyme inhibitors.
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