2-Phenylpiperazine dihydrochloride is primarily utilized in pharmacological research as a key intermediate in the synthesis of various biologically active compounds. It plays a significant role in the development of psychoactive drugs, particularly those targeting the central nervous system. The compound is often employed in the study of serotonin and dopamine receptors, aiding in the creation of potential treatments for psychiatric disorders such as depression, anxiety, and schizophrenia. Additionally, it is used in the design of ligands for receptor binding assays, helping to elucidate the mechanisms of action of neurotransmitters and their pathways. Its application extends to the synthesis of novel therapeutic agents with potential analgesic or antipsychotic properties.