1-Boc-4-(2-nitrophenyl)piperazine

≥97%

Reagent Code: #173472
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CAS Number 170017-73-9

science Other reagents with same CAS 170017-73-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 307.34 g/mol
Formula C₁₅H₂₁N₃O₄
badge Registry Numbers
MDL Number MFCD08275017
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used in organic synthesis as a protected piperazine building block for pharmaceutical development. The Boc (tert-butoxycarbonyl) group allows for controlled deprotection under mild acidic conditions, enabling stepwise construction of complex molecules. The 2-nitrophenyl substituent can act as a directing group or be reduced to an aniline derivative, which is valuable for forming amide or sulfonamide linkages common in bioactive compounds. Frequently employed in the synthesis of drug candidates targeting central nervous system disorders and kinase inhibitors due to the piperazine scaffold’s prevalence in such therapeutics. Its structure supports combinatorial chemistry approaches in medicinal chemistry research.

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Test Parameter Specification
Appearance Light yellow to brown solid
Purity (%) 97-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿148.50
inventory 5g
10-20 days ฿726.00
inventory 25g
10-20 days ฿6,450.00
inventory 1g
10-20 days ฿154.00

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1-Boc-4-(2-nitrophenyl)piperazine
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Used in organic synthesis as a protected piperazine building block for pharmaceutical development. The Boc (tert-butoxycarbonyl) group allows for controlled deprotection under mild acidic conditions, enabling stepwise construction of complex molecules. The 2-nitrophenyl substituent can act as a directing group or be reduced to an aniline derivative, which is valuable for forming amide or sulfonamide linkages common in bioactive compounds. Frequently employed in the synthesis of drug candidates targeting central nervous system disorders and kinase inhibitors due to the piperazine scaffold’s prevalence in such therapeutics. Its structure supports combinatorial chemistry approaches in medicinal chemistry research.
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