1-Boc-4-(2-nitrophenyl)piperazine
≥97%
Reagent
Code: #173472
CAS Number
170017-73-9
science Other reagents with same CAS 170017-73-9
blur_circular Chemical Specifications
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Molecular Information
Weight
307.34 g/mol
Formula
C₁₅H₂₁N₃O₄
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Registry Numbers
MDL Number
MFCD08275017
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in organic synthesis as a protected piperazine building block for pharmaceutical development. The Boc (tert-butoxycarbonyl) group allows for controlled deprotection under mild acidic conditions, enabling stepwise construction of complex molecules. The 2-nitrophenyl substituent can act as a directing group or be reduced to an aniline derivative, which is valuable for forming amide or sulfonamide linkages common in bioactive compounds. Frequently employed in the synthesis of drug candidates targeting central nervous system disorders and kinase inhibitors due to the piperazine scaffold’s prevalence in such therapeutics. Its structure supports combinatorial chemistry approaches in medicinal chemistry research.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Light yellow to brown solid |
| Purity (%) | 97-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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