Used primarily as a protected intermediate in the synthesis of pharmaceuticals and biologically active compounds. The Boc-protected piperazine with a hydroxymethyl group allows for selective functionalization, making it valuable in drug discovery, especially in the development of kinase inhibitors, antiviral agents, and CNS-active drugs. The hydroxyl group can be further modified through esterification or ether formation, while the Boc group can be removed under mild acidic conditions to liberate the piperazine nitrogen for further coupling. Commonly employed in solid-phase and solution-phase peptide-like synthesis where controlled reactivity is required.