AS-252424 is primarily used in research settings as a selective inhibitor of the PI3Kγ (phosphoinositide 3-kinase gamma) enzyme. Its application is significant in studying inflammatory diseases and cancer, as PI3Kγ plays a crucial role in cell signaling pathways related to immune response and tumor growth. Researchers utilize AS-252424 to investigate the potential therapeutic effects of PI3Kγ inhibition, particularly in conditions like rheumatoid arthritis, asthma, and certain cancers. By blocking this enzyme, it helps in understanding the underlying mechanisms of these diseases and aids in the development of targeted treatments. Additionally, it is employed in preclinical studies to evaluate its efficacy and safety as a potential drug candidate.