TG 100801 is primarily utilized in the field of biomedical research, particularly in the study of cellular signaling pathways. It serves as a potent and selective inhibitor of PI3K (phosphoinositide 3-kinase) and mTOR (mechanistic target of rapamycin) pathways, which are critical in regulating cell growth, proliferation, and survival. Researchers employ TG 100801 to investigate the roles of these pathways in various diseases, including cancer, where aberrant PI3K/mTOR signaling is often implicated. By inhibiting these pathways, TG 100801 helps in understanding their mechanisms and in evaluating potential therapeutic strategies. Additionally, it is used in preclinical studies to assess the efficacy of targeting PI3K/mTOR in tumor models, aiding in the development of novel anticancer drugs.