EMD638683 R-Form is primarily utilized in research and development within the pharmaceutical and biomedical fields. It acts as an activator of AMP-activated protein kinase (AMPK), with applications focused on studying and modulating biological pathways related to metabolic disorders, including glucose and lipid metabolism, insulin sensitivity, and inflammation. Researchers use this compound to investigate its potential effects in treatments for type 2 diabetes and other insulin resistance-related conditions. Additionally, it serves as a reference compound in preclinical studies to understand its mechanism of action and efficacy in targeting enzymes involved in metabolic regulation. Its role is critical in advancing knowledge and developing novel therapeutic strategies.