AUY954 is a potent and selective antagonist of the sphingosine-1-phosphate receptor 1 (S1P1). It is primarily used in research to study the role of S1P1 signaling in lymphocyte trafficking and immune cell migration from lymphoid organs. AUY954 is employed in preclinical models to investigate its effects on autoimmune diseases, such as multiple sclerosis, inflammation, and immune regulation. Researchers utilize it in in vitro and in vivo experiments to explore its mechanism of action, including inhibition of lymphocyte egress, and to assess its potential as a therapeutic agent for immune-mediated disorders. Pharmacological studies with AUY954 also evaluate its bioavailability, pharmacokinetics, and safety profile.